Home Contact Us Site Map
Search for:
Mercy Babies Classes News
Health Info Find a Job Find a Physician
Mercy Health Center
Oklahoma City
Mercy Memorial
Health Center

Ardmore
Mercy Health
Network Clinics

Oklahoma City
Mercy NeuroScience
Institute

Oklahoma City
Oklahoma
Heart Hospital

Oklahoma City
 
Home > Neuroscience Institute 

NeuroScience Institute

Multiple Sclerosis Center of Oklahoma
Clinical Trials

Ongoing clinical trials

  1. CLARITY (IMP 25643)
    Safety and efficacy of oral cladribine in relapsing-remitting MS.

  2. FREEDOMS II (FTY720 D 2309)
    Efficacy and safety of two different doses of fingolimod (oral preparation) in relapsing-remitting MS.

  3. Tysabri vaccine (10-MS-404)
    Effect of natalizumab on vaccination response and lymphocyte subsets.

  4. Allegro (MS-LAQ-301)
    Safety, tolerability and efficacy of oral laquinamod in relapsing-remitting MS.

  5. BALTUS
    Assessment and treatment of postural imbalance in MS.

  6. Arterial elasticity
    Evaluation of the effects of CNS inflammation in peripheral arterial elasticity in subjects with MS.

  7. TYGRIS
    Tysabri global observational program.

 

Upcoming trials

  1. Safety, tolerability, and neuroprotection of atacicpet assessed by optical coherence tomography (OCT) in optic neuritis as clinically isolated syndrome (CIS)

  2. Efficacy and safety of NG 00012 (dimethyl fumarate) in relapsing remitting MS, using glatiramer acetate as active reference.

  3. Efficacy and safety of two different doses of teriflunamide in patients with relapsing-remitting MS using interferon beta 1a subcutaneous as a calibrator.

  4. Two annual cycles of intravenous low and high dose alemtuzumab compared to three-times weekly subcutaneous interferon beta 1a.

Publications and abstracts

Safety and immunogenicity of interferon beta 1a in a phase IIIb study in patients with relapsing MS: 48 week results. Multiple Sclerosis. 13: S53, 2007

Impact of oral antihistamine on local injection site reactions with glatiramer acetate. Multiple Sclerosis. 13: S134, 2007

Rebif New Formulation (RNF; interferon beta 1-a): 1-year results of a phase IIIb study in patients with relapsing forms of multiple sclerosis. Journal of Neurology. 254(S3): 15, 2007

Immunogenicity and tolerability of Interferon Beta 1a (Rebif New Formulation): 24 and 48 week interim analyses of 2-year, open-label, historically controlled, Phase IIIb study in adults with Multiple Sclerosis. Clinical Therapeutics. 29(6): 1128-1145, 2007.

Safety and immunogenicity of Rebif New Formulation (RNF) a new subcutaneous formulation of interferon beta-1a 44 mcg three times weekly: 1-year results of a phase IIIb study in patients with relapsing multiple sclerosis. Neurology. 68 (12) S1: A274, March 2007.

Reduced immunogenicity with a new formulation of interferon beta 1a (Rebif): 24-week results of a phase IIIb study. Multiple Sclerosis. 12: S192, 2006.

A study model to investigate adherence to treatment among patients with relapsing-remitting multiple sclerosis initiating therapy with glatiramer acetate via pre-filled syringe. Multiple Sclerosis. 11(S1): s83, 2005

The role of self-efficacy in predicting adherence to glatiramer acetate in pre-filled syringes among patients with and without prior treatment experience with immunomodulatory therapy. Multiple Sclerosis. 11(S1): S83, 2005.

Predicting adherence to therapy with glatiramer acetate administered with pre-filled syringes in patients with relapsing-remitting multiple sclerosis. Multiple Sclerosis. 11(S1): S83, 2005.

Multiple Sclerosis and Optic Neuritis. Focal Points. American Academy of Ophthalmology. 2004.

 

 

 

A member of the
Sisters of Mercy Health System