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For Immediate Release


September 8, 2004

Leading Oklahoma in Heart Research

Oklahoma City—Oklahoma Heart Hospital is among the nation’s first hospitals and the only hospital in Oklahoma taking part in an international clinical trial of a drug-coated stent in a cardiac patient.

Although stents have been available for many years, drug-coated stents are new to the market. Bare metal stents serve as tiny metal scaffolds that help keep arteries open, but over time many patients need additional procedures because the arteries tend to clog up again due to scar tissue. Drug-coated stents help prevent arteries from getting plugged up with tissue.

“Boston Scientific did a study that involved more than 1,300 patients and only 3 percent of those with a drug-coated stent needed a second procedure within nine months, in contrast to 11 percent who received a bare-metal stent,” said Dr. Thomas McGarry, an Oklahoma Cardiovascular Associates’ interventional cardiologist and the principal investigator in the stent research. “For patients, placing a drug-coated stent versus undergoing a bypass operation translates to less trauma and a shorter recovery time.”

Instead of a standard eight- to 10-inch incision in the chest for bypass surgery, angioplasty and stents only requires a small opening in the femoral artery in the groin. Through the groin opening, physicians guide a tiny balloon to a blockage near the heart, then inflate it to unclog the artery. As the balloon expands, the stent does as well.

The Liberté stent, made by Boston Scientific Corp., is coated with a chemotherapy drug called paclitaxel that helps prevent tissue growth inside the stent. Almost three years ago, Oklahoma Foundation for Cardiovascular Research—supported by Oklahoma Cardiovascular Associates and Oklahoma Heart Hospital—participated in early research of this type of stent. This is the first drug-eluting stent trial using a second-generation stent.

“With Oklahoma ranking second in the nation in deaths due to heart disease, it’s critical that the Oklahoma Heart Hospital continues to lead the state in cardiovascular research and technology,” said Dr. McGarry. “We continue to be committed to bringing the latest medical advances to our state in diagnosing and treating heart disease.”

Oklahoma Heart Hospital, the first all-digital hospital in the nation, is a partnership between Oklahoma Cardiovascular Associates and Mercy Health Center, along with other cardiovascular physicians.
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